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JCI Insight 1 , e90045 (2016)

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Following this blockade, use of high (but sublethal) concentrations of Zn in rodent cortex can cause a Src kinase-mediated up-regulation of NMDA receptor activity and subsequent cytotoxicity (278)

The method of embodiment75, wherein the composition comprises between about 0.01% to about 20% by weight of the cholesterol, about 0.01% to about 15% by weight of the cholesterol, about 0.01% to about 10% by weight of the cholesterol, about 0.01% to about 7% by weight of the cholesterol, about 0.01% to about 5% by weight of the cholesterol, about 0.01% to about 3% by weight of the cholesterol, about 0.01% to about 2% by weight of the cholesterol, or about 0.01% to about 1% by weight of the cholesterol