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When ROS levels outpace the bodys natural defense systems, it leads to lipid peroxidation, which causes premature muscle fatigue and a drop in power output

It is a member of the growth hormone-releasing peptide family and works by stimulating the ghrelin receptor, which then releases growth hormones from the pituitary gland

Owing to their high oxygen consumption, skeletal muscle fibers are inherently prone to ROS generation during contraction and metabolism ( Elevated ROS also activate the NF-B pathway by depleting glutathione (GSH), downregulating myogenic transcription factors (MyoD, MyoG), and upregulating the transcriptional repressor Yin Yang 1 (YY1), thereby impairing myogenic differentiation (Xiang et al., 2022)