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Referral to a dermatologist or immunologist is important for people with chronic or recurrent urticaria

Similarly, oxidative stress states such as sepsis and critical illness can predispose to pyroglutamate accumulation due to increased GSH demand driven by elevated reactive oxygen species production [65]

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Hum Genet 126:5190 Gold JM, Waltz JA, Matveeva TM et al (2012) Negative symptoms and the failure to represent the expected reward value of actions: behavioral and computational modeling evidence