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Abstract Alterations in excitatory neurotransmitters, involving the glutamate (Glu) and glutamine (Gln) cycle, as well as inhibitory neurotransmission, GABA, are implicated in the pathophysiology of autism spectrum disorder (ASD)

In some embodiments, the auris-acceptable penetration enhancer is a surfactant comprising an alkyl-glycoside wherein an oxygen atom within the alkyl-glycoside is substituted with a sulfur atom

It also plays a vital role in the synthesis of collagen, a protein found in connective tissues, skin, blood vessels and bones

The anti-inflammatory and collagen-supporting effects address multiple aspects of aging-related hair changes