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Kirova DG, Judasova K, Vorhauser J, Zerjatke T, Leung JK, Glauche I, et al

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[1] The research, published in a peer-reviewed journal, shows that paraxanthine not only enhanced memory and cognitive function more effectively than caffeine, but also triggered beneficial changes in key brain chemicals and markers of neuroplasticity

Why there should be such striking differences in genetically identical individuals, in a disease caused by the same mutation, is unknown, but likely involves important epigenetic and environmental influences