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In Forbes Magazine online, www.forbes.com /sites/ natalierobehmed/2013/09/17/e-cigarette-sales-surpass-1-billionas-big-tobacco-moves-in Accessed 15/12/2014

For those already at high-risk, smoking raised the chance of worse outcomes from 13.8-fold to 64.2-fold, compared with those in the low-risk reference group

Methods Long-term CSE exposed human bronchial epithelial cell culture BEAS-2B cells were grown in RPMI 1640 (Lonza, Walkersville, MD) supplemented with 15% heat-inactivated Fetal Bovine Serum (FBS), penicillin (100 U/ml) (Lonza) and streptomycin (100 g/ml) (Lonza) on collagen-coated plates

But you can't ignore the influence of e-cigarettes either