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Although the design of this study was not ideal with respect to current practice paradigms, it did support the notion that early use of anti- TNF therapy led to better outcomes than the traditional approach of using corticosteroids first, immunomodulators second, and then anti-TNF agents

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Unlike full-length growth hormone, AOD-9604 does not upregulate IGF-1, does not induce insulin resistance in reported toxicology models, and does not measurably affect linear growth in adult animal models