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It walks through pathways in plain language

SKIN-LIGHTENING EFFECT The role of glutathione as a skin-lightening agent was accidentally discovered as a side effect during treatment of chronic diseases with glutathione.[] Various mechanisms have been proposed

Astaxanthin protects against MPP+-induced oxidative stress in PC12 cells via the HO-1/NOX2 axis

Importantly, since both glutamate export and cysteine import via system XcT are tightly linked to ferroptosis regulation, changes in glutamate or cysteine availability resulting from altered 5-OP metabolism could significantly impact cellular susceptibility to oxidative stress (Figure 3E)