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Keep unopened vials frozen, reconstitute with bacteriostatic water only when a study calls for it, and refrigerate the reconstituted solution for short-term use

First, astrocytes protect neurones in the penumbra, and second, after the end of infarct expansion, astrocytes form a peri-infarct barrier very similar to the perilesional barrier in the TBI

in the ultrasonicator operating system) to facilitate complete cell lysis and tissue homogenization

Albeit, such macrophage ablation studies must be interpreted with caution, as in a recent study, the anti-inflammatory effects of clodronate liposomes in arthritis models were attributed to the modulation of neutrophil effector functions after phagocytosis of liposomes (103)