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Articles were also excluded from the analysis when their methods and definitions had been superseded by new scientific evidence

Nanoscale 7 (45), 1891818922

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[7] The SU.VI.MAX randomized placebo-controlled trial showed a reduction in cancer risk and all-cause mortality among men taking an antioxidant cocktail (low doses of vitamins C and E, beta-carotene, selenium, and zinc) but no apparent effect in women, possibly because men tended to have low blood levels of beta-carotene and other vitamins at the beginning of the study