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11 Female Hormonal (Menstrual) Cycle Female fertility is controlled by cyclic hormone signals from the hypothalamus and pituitary gland via the hypothalamic-pituitary-ovarian (HPO) axis

In several RCTs, GLP-1RAs, when used alone or in combination with other hypoglycemic agents including metformin, sulfonylurea, DPP-4 inhibitor, thiazolidinedione, and sodium-glucose cotransporter 2 inhibitor, showed superior or non-inferior blood glucose lowering ability compared to insulin treatment [64,65]

Targeted metabolomics analysis shows that 5FU treatment promotes significant changes in metabolite abundance over time (Fig

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