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It was noted that there was significant association between intermediate and poor metabolizers of CYP2D6 and CYP2C19 and tamoxifen resistance [75]

injection Duration of action is ~ 1 hour with typical doses, up to 6 hours with high doses

Individuals with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia type 2 (MEN2) should discuss this with their clinician before considering any GLP-1based therapy, and should be alert to symptoms such as a neck lump, hoarseness, or difficulty swallowing