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In addition, activation of the NADPH oxidase is linked to changes in the structure and function of cerebral arterioles that are associated with small vessel disease [49], and to angiotensin II-dependent activation of the enzymatic complex that increased oxidative stress and hypertension in both rats and endothelial cells [43]

Leaders are picking up on this idea: 16 percent of employers provide a discount on health insurance premiums to people who do not use tobacco products, and 10 percent offer a discount for participating in a program to quit smoking, according to the Society for Human Resource Managements (SHRMs) 2018 Employee Benefits survey report