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However, not every patient is an ideal candidate for TRTespecially those concerned about preserving fertility or wanting to

First, it disrupts the process of melanin synthesis by inducing the release of high mobility group box 1 (HMGB1) protein, thus downregulating the melanin biosynthesis-related proteins: melanocyte-inducing transcription factor, tyrosinase, tyrosinase-related protein-1, tyrosinase-related protein-2, RAB27A and fascin actin-bundling protein 1 [17, 18]

Ensuring levels are within a healthy range is vital, as excess magnesium from supplements can cause adverse effects such as gastrointestinal discomfort or more serious electrolyte imbalances

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