Other metabolites may also mediate the secretion of inflammatory cytokines and are involved in the inflammatory pathway of RA
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The weight of these pre-clinical data, together with congruent findings in large animals and early human studies, underpins growing optimism that cellular regeneration can close the gap left by cryopreservation, GnRHa co-therapy and hormone replacement, all of which safeguard parenthood options but do little to repair endogenous ovarian function [169]