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(Patient education monograph)

A randomized, double-blind, placebo-controlled trial in 191 older adults (75 years) with moderate vitamin B 12 deficiency (serum cobalamin concentrations of 107-210 pmol/L) without anemia provided participants with 1 mg/day of cyanocobalamin for one year (94)

NNMT inhibition via 5-Amino-1MQ was associated with higher NAD+ levels, thereby influencing sirtuin activation and mitochondrial function

All clinical decisions regarding patient eligibility, dosing, monitoring, and treatment should be made by a licensed healthcare provider based on the individual patients clinical presentation, medical history, and applicable standard of care