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For the samples, the severity of the subcutaneous tissue necrosis was assessed by a trained toxicopathologist using a light microscope and scored on a numerical scale, where code 1 reflects no abnormalities and code 5 reflects marked severity: 1 , no abnormalities 2, minimal severity 3, mild severity 4, moderate severity 5, marked severity Results on scores of necrosis are shown in table 24a and table 24b

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Why it was included in the FDA ban Semax has a high risk of immune reactions and impurities during the compounding process