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miR-324 directly targeted the hepatic ROCK1 3 untranslated region (3UTR), downregulated ROCK1 protein, and upregulated phosphorylated AKT (p-AKT)/GSK3 (p-GSK3) to activate insulin signaling, improving hepatic glucose-lipid metabolism

It is possible to sustain a tendon injury through various activities from work to contact sports, and onset can be gradual or sudden

Immunofluorescent (IF) staining of K1 cells was performed and revealed a significant increase in TfR1 protein expression compared to DMSO-treated control cells (RSL3 94.7% vs

Taken together, these findings suggest that NSBSO-induced GSH depletion and synthesis inhibition can elevate intracellular ROS, thereby activating the caspase family, leading to GSDME cleavage and cell pyroptosis