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38,39 However, the Wnt/-catenin signalling pathway is not only positively activated by the above factors but also inhibited by many negative feedback regulators, such as Notum, Tiki, DKKs, Wise/SOST, IGFBP-4, sFRPs, WIF1, and ZNRF3/RNF43

Melanocytes on these cells produce and distribute melanin (a pigment that determines our natural hair color) which is then transferred to the keratinocytes that make up the cells in the hair shaft

Since apoptosis is defined by the NCCD as a caspase-dependent RCD [4], and considering the fact that eryptotic pathways dont culminate in activation of caspases [84], it has become clear that eryptosis is guided and executed alternatively