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HemaniGZhengJElsworthBWadeKHaberlandVBairdDet al

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The case for stacking them rests on a single observation: the four receptor systems involved GLP-1, GIP, glucagon, and amylin are all non-overlapping

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Key risks include lean muscle mass loss, heart rate elevation, pancreatitis, gallbladder disease, hypoglycaemia, and acute kidney injury from dehydration

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All work is non-clinical and mechanistic in nature

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