Zhou, N, Bott, M, Park, B, Vallieres, E, Wilshire, CL, Yasufuku, K, Spicer, JD, Jones, DR, Sepesi, B, Mitchell, KG, Corsini, EM, Antonoff, MB, Hofstetter, WL, Mehran, RJ, Rice, DC, Swisher, SG , Vaporciyan, AA, Walsh, GL, Huynh, C, Fiset, PO, Chun, SG, Gay, CM
Furthermore, cytokine profile have been correlated with ASD severity: in children with moderate to mild ASD, IL-12p40 were found to be increased while higher levels of tumor necrosis factor alpha (TNF-) were found in children with moderate severity (Inga Jcome et al., 2016)
therefore, viral hijack of this proprotein convertase enzyme could alter lipid metabolism, and affect blood pressure regulation and vascular remodeling in COVID-19 patients 344,345
Studies suggest glutathione replacement might help relieve complications of systemic lupus erythematosus by reducing autoantibody levels and regulating T-cell function