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Key Cellular and Molecular Events Fibroblasts, keratinocytes and macrophages Fibroblasts play a vital role in repairing the wound because they are involved in producing collagen, fibronectin and proteoglycan which constitute the extracellular matrix

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A 2025 Nature Communications paper mapped the binding to the disordered transactivation domain of p53, adding structural detail to how FOXO4-DRI engages its target

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