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Description

AD is a complex, progressive neurodegenerative disorder characterized by cognitive decline, amyloid-beta (A) plaques, and tau protein neurofibrillary tangles

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TAR DNA-binding protein 43 (TDP-43) and FUS (fused in sarcoma) Research has identified the cellular protein TDP-43 as an important factor in the cause of ALS, especially the sporadic forms (Mackenzie 2007)

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Abogadallah et al

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