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Immunosuppressive effect of geniposide on mitogen-activated protein kinase signalling pathway and their cross-talk in fibroblast-like synoviocytes of adjuvant arthritis rats

For patients with neurological involvement, maintenance injections are typically given every 2 months

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Lastly, Wijesinghe et.al highlight the significance of obesity in both load-bearing and non-load bearing joints in changing the inflammatory molecular endotype OA synovial fibroblasts, providing a rational for the therapeutic targeting of specific synovial fibroblasts subsets in specific patient populations with arthritic conditions [68]