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A total of 200 M hydrogen peroxide (H 2 O 2 ) significantly induced cytotoxicity in HeLa cells, while H 2 O 2 up to 300 M did not induce cytotoxicity in HepG2 cells, further demonstrating the strong resistance of HepG2 cells to ROS

This tends to lead to longer recovery times and higher blood loss

LabCorp website

For instance, dihydroartemisinin (DHA) was shown to induce UPR feedback that attenuates ferroptosis via the PERK/ATF4/HSPA5 pathway in glioma cells, suggesting that stress responses can modulate GPX4 activity and ferroptotic sensitivity