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NADPH: reduced nicotinamide adenin dinucleotide phosphate

Participants were matched by total body mass and then randomly assigned a supplementation protocol, in double-blind fashion, consisting of the oral ingestion of either 200 mg/day of GSH + 2 g/day of L-citrulline [GSH + CIT ( n = 25)], 2 g/day of L-citrulline-malate [CIT-malate ( n = 25)], or 2.52 g/day of cellulose placebo ( n = 25)

Evidence remains largely preclinical, with growing interest in translational applications for aging, metabolic disorders, and neurodegeneration

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