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Upon mitochondrial depolarization, PINK1 accumulates on the outer mitochondrial membrane and initiates a phosphorylation cascade in which PINK1 phosphorylates PRKN and ubiquitin to promote PRKN activation and ubiquitin-dependent signaling on damaged mitochondria 12,13

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In no particular order, here are the six runners-up: "Bae" "Bae" is "a term of endearment for a romantic partner." Oxford's blog says the term "probably has more currency" in the U.S

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