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Oligodendrocytes also enhance BBB integrity, but treatment with antagonists of platelet-derived growth factor receptor does not impair oligodendrocyte-induced BBB integrity [98]

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Children's requirements are lower and increase with age: infants aged 0-6 months have a safe intake of about 0.3 g daily, those aged 712 months need 0.4 g daily, children aged 13 years require 0.5 g, those aged 46 years need 0.8 g, and children aged 710 years should receive 1.0 g daily