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2 shows, treatments with 3 or 10 mM of either reagent reduced the oligomerization/dimerization levels of secreted L68Q-hCC in vitro

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Notably, reactive astrocytes closely interact with A plaques and degrade A plaques in an apolipoprotein E epsilon 4 (APOE) gene-dependent manner by releasing amyloid-degrading enzymes such as insulin-degrading enzyme (IDE) and matrix metalloproteinases (MMP-2, MMP-9) 48,49

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