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The second nuclear estrogen receptor, ER, also binds tamoxifen and its metabolites with similar affinities 12

Understanding these reverberations will increase our insight into the basic biology of the effects of SARS-CoV-2 infection on the various organ systems

Then, deciphering the gut microbiota-butyrate-ferroptosis crosstalk in the gut-joint axis is vital to further understanding the whole process, such as the effects of gut microbiota metabolic functions on intra-articular butyrate and the transmission pathway therein

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