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[9] Visual disturbances have been reported in patients with Leber hereditary optic neuropathy, and rapid B12 administration may precipitate optic nerve atrophy in this genetically predisposed population, mandating extreme caution or alternative therapy

In some countries neonatal screening programs are established as part of the strategy for prevention of severe neonatal jaundice

As a general rule, IM is favored when the goal is rapid correction of a clinical deficiency, when the patient has difficulty absorbing B12 through oral or sublingual routes, or when a provider wants predictable peak serum levels

Per the FY2026 ICD-10-CM Official Guidelines for Coding and Reporting, providers must assign the most specific code supported by documentation, which is why a lingering anemia unspecified icd 10 assignment invites review