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In the synthesis method of cagrilinteide, the Vc reagent is prepared by dissolving Vc per gram in 20-30mL of purified water
Pharmacodynamic synergy in medicinal plants occurs through various mechanisms that include action on multiple targets such as improved bioavailability, potentiation of effect, or modulation of side effects
This is because the elevated glycine would disrupt the interactions between GcvR and GcvA and allow expression of the glycine biosensor to occur (reaction 4), whereas there is no elevated glycine in reaction 5 so this interaction would not be disrupted
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