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Amino Acids, 31 , 251-272

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Furthermore, the current UA elevation therapy shows unstable antioxidant properties, individual variability, and potential adverse effects, thus restricting its clinical applications [14]

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13 These histone acetyltransferase proteins facilitate the remodeling of histones within chromatin and further increase the transcriptional activity of PGC-1s

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GHK-Cu has been investigated as an activator of SOD1 and as a modulator of the Nrf2-Keap1 antioxidant response pathway in cellular models

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