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The original online version of this Article was revised: The original version of this Article contained errors in Figure 7A, where the X-axis labels of the bar graphs were incorrectly labelled as Con, Si, Con-DSS and Si-DSS (from left to right)

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3 Results 3.1 Metabolome analysis reveals dominant impact of SLE on the pentose phosphate pathway, nucleotide, cysteine, and kynurenine metabolism Quantitative enrichment analysis of 258 measured metabolites revealed robust changes in the metabolome of SLE patients PBL relative to those of healthy controls matched for age within 10 years, gender, and ethnic background