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All hypertensive patients had no clinical signs, symptoms and laboratory findings suggesting secondary hypertension

43 The relevance of this pathway for tumorigenesis is demonstrated by the fact that humans with the Laron syndrome, a recessively inherited defect in the growth hormone receptor, display extremely low IGF-1 and reduced insulin concentrations and usually do not develop cancer despite high prevalence of obesity and dyslipidemia

10.1080/09603123.2023.2210109 159 NarkwicheanA.MaaloufW.BaumgartenM.PolanskiL.Raine-FenningN.CampbellB.et al (2017)

Oh yeah, you know, there's some great ones, but they're few and far between