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Springer International Publishing: Cham, 2017
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The association of ROS with neuronal degeneration in PD is further substantiated by modeling the Parkinsonian phenotypes in animals through 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), rotenone, 1,1-dimethyl-4,4-bipyridinium dichloride (paraquat), or 6-hydroxydopamine (6-OHDA), those are known of elevate the oxygen free-radicals in the cell 18
Different viruses, including the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) 26 , influenza A virus (IAV) 21,27,28,29 , herpes simplex virus (HSV) 22 , hepatitis C virus (HCV) 30,31,32 , human immunodeficiency virus-1 (HIV-1) 33 , respiratory syncytial virus (RSV) 34 , and enterovirus (EV)-71 35 , induce ROS generation during infection
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