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Although the thioredoxin and glutaredoxin systems are both found in the chloroplast stroma (Rouhier et al., in vitro redox-midpoint of GCL (Hicks et al., Plant Glutathione Synthetases: Structure, Function, and Product Diversity In the second step of glutathione synthesis, GS catalyzes the ATP-dependent addition of glycine to -glutamylcysteine (Figure 1)
It is reported that omega-3 fatty acids inhibit the oxidation of polyunsaturated long-chain fatty acids and boost the antioxidant and anti-inflammatory effects of other nutrients (162)
Piperlongumine Piperlongumine (PL) is an alkaloid isolated from Piper species, commonly used in traditional medicine in particular in Asia and Latin America that in recent years has been extensively studied because of its anti-cancer potential, being able to inhibit proliferation in several cancer cell lines 107
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