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853 The HDX-MS reveal unfolding of the G2 loop specifically upon GTP hydrolysis, which impacts the stability of selected other regions of Ab ZigA, extending into the CTD (Figure 48B)

Towards the end of the article, theres a really beautiful, simple image, figure one, now that Im looking back at it, of just the different positions that you might see somebody put their self into for different lifts and why one is going to hurt their back and one isnt going to