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Ultra-high IV doses of methyl B12 (25mg) were shown safe and potentially effective for patients with peripheral neuropathy and chronic axonal degeneration

Oral Supplements : Oral supplements are widely available, and research suggests that, at high doses, they can be just as effective as injections for correcting deficiency[21], making them a viable alternative for many individuals

Permeability in the small intestine is assessed with L-rhamnose and lactulose as per the dual sugar test, whilst in the colon this can be assessed with the non-fermented erythritol and sucralose