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The apparent lack of a direct effect was noted due to the in vitro environment not mimicking the inherent environment of a tendon in vivo

The NHS schedule for treating B12 deficiency is a loading dose of 1mg hydroxocobalamin by intramuscular injection every two to three days for two weeks, then a maintenance dose every two to three months for life when the cause is non-dietary

For comparison, its lower than an average cyanocobalamin injection price (~$5 at local US pharmacies)

That anti-inflammatory component is particularly relevant for our patient population in Doral, where Fitzpatrick III-V skin types require a treatment approach that produces repair without triggering the melanocyte response