This hypoxic and acidic microenvironment in metabolically altered GBMs affects radiotherapy efficacy and drug delivery, and plays a crucial role in biological mechanisms involved in cancer progression and treatment resistance, such as aberrant DNA repair, angiogenesis, and cancer stem cell maintenance [5,6,7,8,9,10]
Intravenous administration provides a direct, and therefore more reliable, route of systemic drug delivery
10.15436/2378-6841.17.1551 Summary Keywords anxiety, depression, PTSD, GWI, glutamate, diet, intervention Citation Brandley ET, Kirkland AE, Baron M, Baraniuk JN and Holton KF (2022) The Effect of the Low Glutamate Diet on the Reduction of Psychiatric Symptoms in Veterans With Gulf War Illness: A Pilot Randomized-Controlled Trial
Both chronic stress and fatigue are directly linked to a deficiency of the key nutrient, vitamin B12