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[DOI] [PMC free article] [PubMed] [Google Scholar] Monod J

The original paper is in Mandarin and you can access it here (paywall): #Type2Diabetes #DiabetesResearch #Obesity #GLP1 #Semaglutide #Dorzagliatin #MetabolicHealth #HuaMedicine To view or add a comment, sign in A newly published peer-reviewed scientific paper from China adds to the growing body of evidence around the benefits that dorzagliatin (GKA) in combination with the popular semaglutide (GLP-1RA) delivers superior glycemic control, weight reduction, and islet cell function improvement when compared with semaglutide monotherapy in obese patients with Type 2 diabetes mellitus (T2DM), with a comparable safety profile

Repeated stimulation likely downregulated Trpa1 , a common adaptive mechanism to sustained receptor activation 73 that may modulate the excitability and peptide turnover of EWcp/UCN1/CART neurons, potentially influencing alcohol consumption pattern

10002000 g daily) can correct deficiency in some cases (even without intrinsic factor, because a small fraction can be absorbed passively)