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Humanized mAb Olokizumab (CDP6038), or OKZ, binds to the IL-6 receptor and showed favorable results in phase III with a significant reduction in DAS28 from baseline after 12 weeks of treatment [104]

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Results Immunolocalization of the Reduced Form of Glutathione in Wild-Type and Mutant Nodules In wild-type nodules (Figures 1AC), GSH was detected in the cytoplasm and nuclei of meristematic cells (Figures 1DF), the cytoplasm and nuclei of infected cells in the infection zone (Figures 1GI), the cytoplasm and symbiosomes of cells in the nitrogen fixation zone (Figures 1JL), and cells of the nodule parenchyma and vascular tissue (Figures 1AC)

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