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Single-cell nuclear transcriptomics studies of the brain suggest that NPs may induce Parkinsons disease-like neurodegenerative lesions by disrupting mitochondrial energy metabolism and adenosine triphosphate (ATP) production in substantia nigra and striatal excitatory neurons (Youssef et al., 2021) and exacerbate -synuclein aggregation in SH-SY5Y cells derived from human neuroblastoma, a hallmark of Parkinsons disease (Polinski et al., 2018)

[DOI] [PubMed] [Google Scholar] Fabbri M, Smart C, Pardi R, 2003

In research circles, ipamorelin garners respect for its specificity: it zeroes in on its intended target with minimal deviations, leading many to label it as the most accurate among growth hormone secretagogues

Song SN, Tomosugi N, Kawabata H, Ishikawa T, Nishikawa T, Yoshizaki K