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The addition of ascorbic acid could be considered as a strategy for preventing folate degradation during processing 193,346,365,371,430,431,457,475,477,544,545,546,547,548,549
This highlights the potency and risk of misuse of the compound
The main rationale for cycling rather than continuous use involves conservative safety practices given limited long-term human data, cost management, and theoretical concerns about receptor desensitization with extended exposure
