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132,133,134 Canonical Wnt signalling acts indirectly on -catenin to enhance its stability, allowing it to translocate from the cell surface to the nucleus, thereby linking extracellular signalling to nuclear gene expression regulation through downstream transcriptional machinery (Fig

Subjects applied GSSG 2% (weight/weight [w/w]) lotion to one side of the face and a placebo lotion to the other side twice daily for 10 weeks

MONTH 2 3+ Studies suggest fine lines and elasticity benefits become more apparent with consistent daily use

This spatial resolution is critical for understanding how oxidative stress affects distinct cellular compartments in preclinical disease models