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Eligible participants in each cohort were randomly assigned in a 3:1 ratio to receive a once-weekly subcutaneous cagrilintide or matched placebo, in combination with a once-weekly subcutaneous semaglutide 24 mg, independent of lifestyle interventions

Its still in clinical trials

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For superior sagittal sinus pressure recording, we made a single burr hole in the rostral part of the sagittal suture, above the superior sagittal sinus, and cannulated superior sagittal sinus anterior part by Braun intravenous cannulas, and then, we laparatomized rats for portal vein, inferior vena cava and abdominal aorta pressure recording