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Prescription sleep medications often focus on sedation

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* Correspondence: Yuzhen Wang, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Since the pKa of Sec is ~ 5.2, the selenol (RSeH) of Sec exits in selenolate (RSe ) form under the physiological condition [8, 11,12,13,14,15,16,17,18]