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Increased levels of ROS and lipid peroxidation products and/or decreased levels of antioxidant enzymes, such as superoxide dismutase (SOD) and catalase, and antioxidant compounds, such as glutathione, have been reported in both NAFLD/NASH patients as well as a variety of animal models of NAFLD 9,10,11,12,13,14

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Symptoms can vary between individuals

Indeed, glutathione deficiency is central to alcoholic liver disease (ALD), with a reduction in glutathione one sign of chronic alcohol consumption