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Lastly, although H-based interventions are approaching clinical viability, challenges related to regulatory frameworks, large-scale manufacturing standards, and cost-effectiveness analyses must be thoroughly addressed for broader adoption in nephrology

This inherent stability allows it to remain biologically active for extended periods, a characteristic that makes it suitable for oral administration in research settings, particularly for studies focused on gastrointestinal health

Glutamate excitotoxicity disrupts synaptic transmission and increases intracellular calcium levels, triggering a cascade of neurotoxic effects

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